Preclinical Study of Single-Dose Moxidectin, a New Oral Treatment for Scabies: Efficacy, Safety, and Pharmacokinetics Compared to Two-Dose Ivermectin in a Porcine Model.

• Hlavní autoři: Charlotte Bernigaud (Autor), Fang Fang (Autor), Katja Fischer (Autor), Anne Lespine (Autor), Ludwig Serge Aho (Autor), Dominique Dreau (Autor), Andrew Kelly (Autor), Jean-François Sutra (Autor), Francis Moreau (Autor), Thomas Lilin (Autor), Françoise Botterel (Autor), Jacques Guillot (Autor), Olivier Chosidow (Autor)
• Médium: Kniha
• Vydáno: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Scabies is one of the commonest dermatological conditions globally; however it is a largely underexplored and truly neglected infectious disease. Foremost, improvement in the management of this public health burden is imperative. Current treatments with topical agents and/or oral ivermectin (IVM) ar...