Preclinical Study of Single-Dose Moxidectin, a New Oral Treatment for Scabies: Efficacy, Safety, and Pharmacokinetics Compared to Two-Dose Ivermectin in a Porcine Model.

• Main Authors: Charlotte Bernigaud (Author), Fang Fang (Author), Katja Fischer (Author), Anne Lespine (Author), Ludwig Serge Aho (Author), Dominique Dreau (Author), Andrew Kelly (Author), Jean-François Sutra (Author), Francis Moreau (Author), Thomas Lilin (Author), Françoise Botterel (Author), Jacques Guillot (Author), Olivier Chosidow (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scabies is one of the commonest dermatological conditions globally; however it is a largely underexplored and truly neglected infectious disease. Foremost, improvement in the management of this public health burden is imperative. Current treatments with topical agents and/or oral ivermectin (IVM) ar...