Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy

• Main Authors: Ellen Dees (Author), Paul M. Miller (Author), Katherine L. Moynihan (Author), Ryan D. Pooley (Author), R. Pierre Hunt (Author), Cristi L. Galindo (Author), Jeffrey N. Rottman (Author), David M. Bader (Author)
• Format: Book
• Published: The Company of Biologists, 2012-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system...