Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy

• मुख्य लेखकों: Ellen Dees (लेखक), Paul M. Miller (लेखक), Katherine L. Moynihan (लेखक), Ryan D. Pooley (लेखक), R. Pierre Hunt (लेखक), Cristi L. Galindo (लेखक), Jeffrey N. Rottman (लेखक), David M. Bader (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2012-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

SUMMARY CENP-F is a large multifunctional protein with demonstrated regulatory roles in cell proliferation, vesicular transport and cell shape through its association with the microtubule (MT) network. Until now, analysis of CENP-F has been limited to in vitro analysis. Here, using a Cre-loxP system...