The role of apoptosis in autoantibody production

• Principais autores: E. López-Robles (Autor), D. Herrera- (Autor), R. Herrera-Esparza (Autor), E. Avalos-Díaz (Autor)
• Formato: Livro
• Publicado em: PAGEPress Publications, 2011-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

In normal conditions, the intracellular autoantigens reach the cell surface by apoptosis and are normally cleared by phagocytes without inflammation, nevertheless the lack of depuration of apoptotic material foster the autoantibody production in individuals genetically predisposed, equally defects i...