Hypertensive Rats Treated Chronically With Nω-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology

• Main Authors: Bo Li (Author), Xinglishang He (Author), Shan-Shan Lei (Author), Fu-Chen Zhou (Author), Ning-Yu Zhang (Author), Ye-Hui Chen (Author), Yu-Zhi Wang (Author), Jie Su (Author), Jing-Jing Yu (Author), Lin-Zi Li (Author), Xiang Zheng (Author), Rong Luo (Author), Dorota Kołodyńska (Author), Shan Xiong (Author), Gui-Yuan Lv (Author), Su-Hong Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nω-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide (NO) biosynthesis, results in hypertension and liver injury. This study aimed at investigating the changes of liver lipometabonomics and exploring the underlying mechanisms of liver injury in the L-NAME-treated rats. The male Sp...