Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation

• Ngā kaituhi matua: Paloma Rodriguez (Author), M Isabel Pérez-Morgado (Author), Víctor M Gonzalez (Author), M Elena Martín (Author), Amelia Nieto (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2016-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The genetic diversity of the influenza virus hinders the use of broad spectrum antiviral drugs and favors the appearance of resistant strains. Single-stranded DNA aptamers represent an innovative approach with potential application as antiviral compounds. The mRNAs of influenza virus possess a 5...