Preclinical anti‐angiogenic and anti‐cancer activities of BAY1143269 in glioblastoma via targeting oncogenic protein expression

• Päätekijät: Weifeng Wan (Tekijä), Xin Zhang (Tekijä), Changren Huang (Tekijä), Ligang Chen (Tekijä), Xiaobo Yang (Tekijä), Kunyang Bao (Tekijä), Tangming Peng (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2022-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Glioblastoma angiogenesis is critical for tumor growth, making it an appealing target for treatment development. BAY1143269 is a novel inhibitor of mitogen‐activated protein kinase interacting serine/threonine‐protein kinase 1 (MKN1) and has potent anti‐cancer activity. We identified BAY114...