Epoxyeicosatrienoic Acids and/or Their Metabolites Promote Hypoxic Response of Cells

• Päätekijät: Sachiko Suzuki (Tekijä), Ami Oguro (Tekijä), Mayuko Osada-Oka (Tekijä), Yoshihiko Funae (Tekijä), Susumu Imaoka (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2008-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Epoxyeicosatrienoic acids (EETs), including 5,6-EET, 8,9-EET, 11,12-EET, and 14,15-EET, are produced by cytochrome P450 (P450) such as CYP2C8 and 2C9; and they are hydrolyzed to dihydroxyeicosatrienoic acids (DHETs) by epoxide hydrolase. Particular interest in the epoxygenase reaction has developed...