Cpne1 deficiency preserves sperm motility under Ca2+ channel blockade

• Main Authors: Qiang XIE (Author), Hanbin ZHANG (Author), Yuge ZHUANG (Author), Jinsheng LIU (Author), Zicong HUANG (Author), Xiaoyuan ZHANG (Author), Ke MA (Author), Wenyuan LIU (Author), Minyu XIE (Author), Chuyu HUANG (Author), Xiaojing ZHONG (Author), Feilong CHEN (Author), Feng ZOU (Author), Wansong ZHANG (Author), Chunming QIU (Author), Canbiao SUN (Author), Xiangjin KANG (Author), Zhenguo CHEN (Author), Guofei ZHANG (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Calcium ions (Ca2+) play crucial roles in sperm motility and fertilization. The copine (CPNE) family comprises several Ca2+-dependent phospholipid-binding proteins. Of these, CPNE1 is extensively expressed in mammalian tissues; however, its precise role in testicular development and spermatogenesis...