Influence of Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study

• المؤلفون الرئيسيون: Narmeen Mallah (مؤلف), Maruxa Zapata-Cachafeiro (مؤلف), Carmelo Aguirre (مؤلف), Eguzkiñe Ibarra-García (مؤلف), Itziar Palacios-Zabalza (مؤلف), Fernando Macías-García (مؤلف), J. Enrique Domínguez-Muñoz (مؤلف), María Piñeiro-Lamas (مؤلف), Luisa Ibáñez (مؤلف), Xavier Vidal (مؤلف), Lourdes Vendrell (مؤلف), Luis Martin-Arias (مؤلف), María Sáinz-Gil (مؤلف), Verónica Velasco-González (مؤلف), Adolfo Figueiras (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BackgroundDespite the wide benefits of aspirin and its cost-effectiveness, aspirin prescriptions have been reduced due to idiosyncratic responses in susceptible individuals. Low-dose aspirin and single-nucleotide polymorphisms (SNPs) are independently associated with increased risk of gastrointestin...