Influence of Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study

• Hauptverfasser: Narmeen Mallah (VerfasserIn), Maruxa Zapata-Cachafeiro (VerfasserIn), Carmelo Aguirre (VerfasserIn), Eguzkiñe Ibarra-García (VerfasserIn), Itziar Palacios-Zabalza (VerfasserIn), Fernando Macías-García (VerfasserIn), J. Enrique Domínguez-Muñoz (VerfasserIn), María Piñeiro-Lamas (VerfasserIn), Luisa Ibáñez (VerfasserIn), Xavier Vidal (VerfasserIn), Lourdes Vendrell (VerfasserIn), Luis Martin-Arias (VerfasserIn), María Sáinz-Gil (VerfasserIn), Verónica Velasco-González (VerfasserIn), Adolfo Figueiras (VerfasserIn)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Schlagworte: article
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BackgroundDespite the wide benefits of aspirin and its cost-effectiveness, aspirin prescriptions have been reduced due to idiosyncratic responses in susceptible individuals. Low-dose aspirin and single-nucleotide polymorphisms (SNPs) are independently associated with increased risk of gastrointestin...