Influence of Polymorphisms Involved in Platelet Activation and Inflammatory Response on Aspirin-Related Upper Gastrointestinal Bleeding: A Case-Control Study

• Main Authors: Narmeen Mallah (Author), Maruxa Zapata-Cachafeiro (Author), Carmelo Aguirre (Author), Eguzkiñe Ibarra-García (Author), Itziar Palacios-Zabalza (Author), Fernando Macías-García (Author), J. Enrique Domínguez-Muñoz (Author), María Piñeiro-Lamas (Author), Luisa Ibáñez (Author), Xavier Vidal (Author), Lourdes Vendrell (Author), Luis Martin-Arias (Author), María Sáinz-Gil (Author), Verónica Velasco-González (Author), Adolfo Figueiras (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundDespite the wide benefits of aspirin and its cost-effectiveness, aspirin prescriptions have been reduced due to idiosyncratic responses in susceptible individuals. Low-dose aspirin and single-nucleotide polymorphisms (SNPs) are independently associated with increased risk of gastrointestin...