Dipeptide of ψ-GSH Inhibits Oxidative Stress and Neuroinflammation in an Alzheimer's Disease Mouse Model

• Hauptverfasser: Abbas Raza (VerfasserIn), Wei Xie (VerfasserIn), Kwan-Hyun Kim (VerfasserIn), Venkateshwara Rao Dronamraju (VerfasserIn), Jessica Williams (VerfasserIn), Robert Vince (VerfasserIn), Swati S. More (VerfasserIn)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Supplementation of glutathione (GSH) levels through varying formulations or precursors has thus far appeared to be a tenable strategy to ameliorate disease-associated oxidative stress. Metabolic liability of GSH and its precursors, i.e., hydrolysis by the ubiquitous γ-glutamyl transpeptidase (γ-GT),...