Time-Resolved Effect of Interferon-Alpha 2a on Activities of Nuclear Factor Kappa B, Pregnane X Receptor and on Drug Disposition Genes

Interferon-alpha (IFN-α) is suggested to cause pharmacokinetic drug interactions by lowering expression of drug disposition genes through affecting the activities of nuclear factor kappa B (NF-ĸB) and pregnane X receptor (PXR). The time-resolved impact of IFN-α 2a (1000 U/mL; 5000 U/mL; 2 h to 30 h)...

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Main Authors: Dirk Theile (Author), Lelia Wagner (Author), Cindy Bay (Author), Walter Emil Haefeli (Author), Johanna Weiss (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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