A novel biological activity of praziquantel requiring voltage-operated Ca2+ channel beta subunits: subversion of flatworm regenerative polarity.

<h4>Background</h4>Approximately 200 million people worldwide harbour parasitic flatworm infections that cause schistosomiasis. A single drug-praziquantel (PZQ)-has served as the mainstay pharmacotherapy for schistosome infections since the 1980s. However, the relevant in vivo target(s)...

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Main Authors: Taisaku Nogi (Author), Dan Zhang (Author), John D Chan (Author), Jonathan S Marchant (Author)
Format: Book
Published: Public Library of Science (PLoS), 2009-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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