Design, synthesis and biological evaluation of novel diarylpyridine derivatives as tubulin polymerisation inhibitors
A set of novel diarylpyridines as anti-tubulin agents were designed, synthesised using a rigid pyridine as a linker to fix the cis-orientation of ring-A and ring-B. All of the target compounds were evaluated for their in vitro antiproliferative activities. Among them, 10t showed remarkable antiproli...
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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A1234.567 |
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