Novel 11-Substituted Ellipticines as Potent Anticancer Agents with Divergent Activity against Cancer Cells

• Hoofdauteurs: Charlotte M. Miller (Auteur), Elaine C. O'Sullivan (Auteur), Florence O. McCarthy (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2019-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Ellipticines have well documented anticancer activity, in particular with substitution at the 1-, 2-, 6- and 9-positions. However, due to limitations in synthesis and coherent screening methodology the full SAR profile of this anticancer class has not yet been achieved. In order to address this shor...