Population pharmacokinetic study of pemetrexed in chinese primary advanced non-small cell lung carcinoma patients

• المؤلفون الرئيسيون: Peng Cao (مؤلف), Wei Guo (مؤلف), Jun Wang (مؤلف), Sanlan Wu (مؤلف), Yifei Huang (مؤلف), Yang Wang (مؤلف), Yani Liu (مؤلف), Yu Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The purposes of this study were to identify physiological and genetic factors that contributed to variability of pemetrexed (PEM) exposure and to optimize the dosing regimens for Chinese non-small cell lung carcinoma patients. A prospective population pharmacokinetics (PPK) research was performed in...