Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4

• Main Authors: Lihua Ao (Author), Yufeng Zhai (Author), Chunhua Jin (Author), Joseph C Cleveland (Author), David A Fullerton (Author), Xianzhong Meng (Author)
• Format: Book
• Published: BMC, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract While cardiac functional recovery is attenuated in the elderly following cardiac surgery with obligatory global myocardial ischemia/reperfusion (I/R), the underlying mechanism remains incompletely understood. We observed previously that human and mouse myocardium releases heat shock protein...