What regulates hepcidin in poly-transfused β-Thalassemia Major: Erythroid drive or store drive?
Background: Hepcidin, a key regulator of iron homeostasis, is increased by iron overload and inflammation while suppressed by hypoxia. In spite of iron overload in β-Thalassemia Major (β-TM), a paradoxical decrease in hepcidin is observed. Aim: To assess the opposing effects of enhanced erythropoies...
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Formatua: | Liburua |
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Wolters Kluwer Medknow Publications,
2014-01-01T00:00:00Z.
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Internet
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A1234.567 |
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