Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism

Peptide nucleic acids (PNAs) are synthetic oligonucleotides with many applications. Compared with DNA, PNAs bind their complementary DNA strand with higher specificity and strength, an attribute that can make it an effective polymerase chain reaction clamp. A growing body of work has demonstrated th...

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Bibliographic Details
Main Authors: Christopher S Hong (Author), Chunzhang Yang (Author), Zhengping Zhuang (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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