Baseline extracellular vesicle miRNA-30c and autophagic CTCs predict chemoradiotherapy resistance and outcomes in patients with lung cancer

• Main Authors: Diego de Miguel-Perez (Author), Francisco Gabriel Ortega (Author), Rosario Guerrero Tejada (Author), Antonio Martínez-Única (Author), Christine B. Peterson (Author), Alessandro Russo (Author), Muthukumar Gunasekaran (Author), Andres F. Cardona (Author), Victor Amezcua (Author), Jose Antonio Lorente (Author), Jose Expósito Hernández (Author), Christian Rolfo (Author), Maria Jose Serrano (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Concurrent chemoradiotherapy (cCRT) is the mainstay of treatment for patients diagnosed with locally advanced non-small cell lung cancer (NSCLC). One significant challenge in the effectiveness of this therapy is the potential development of resistance mechanisms, where autophagy up-regulati...