Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models
Genetic mutations underlying neurodegenerative disorders impair ribosomal DNA (rDNA) transcription suggesting that nucleolar dysfunction could be a novel pathomechanism in polyglutamine diseases and in certain forms of amyotrophic lateral sclerosis/frontotemporal dementia. Here, we investigated nucl...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2017-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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