Selective Inhibition of Mammalian DNA Polymerase by Vitamin D2 and D3

• Main Authors: Yoshiyuki Mizushina (Author), Xianai Xu (Author), Chikako Murakami (Author), Toshio Okano (Author), Masaharu Takemura (Author), Hiromi Yoshida (Author), Kengo Sakaguchi (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583-590), the irradiated products of provitamin D2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D and its related compounds inhibited the activities...