Angiogenin promotes angiogenesis via the endonucleolytic decay of miR-141 in colorectal cancer

• Main Authors: Chunhua Weng (Author), Haojie Dong (Author), Rongpan Bai (Author), Jinghao Sheng (Author), Guangdi Chen (Author), Kefeng Ding (Author), Weiqiang Lin (Author), Jianghua Chen (Author), Zhengping Xu (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mature microRNA (miRNA) decay is a key step in miRNA turnover and gene expression regulation. Angiogenin (ANG), the first human tumor-derived angiogenic protein and also a member of the RNase A superfamily, can promote tumor growth and metastasis by regulating rRNA biogenesis and tiRNA production. H...