Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors

• Главные авторы: Gabriele A. Berwaldt (Автор), Daniela P. Gouvêa (Автор), Daniel S. da Silva (Автор), Adriana M. das Neves (Автор), Mayara S. P. Soares (Автор), Juliana H. Azambuja (Автор), Geonir M. Siqueira (Автор), Roselia M. Spanevello (Автор), Wilson Cunico (Автор)
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• Опубликовано: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Предметы: article
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A series of nineteen benzothiazin-4-ones from N-(3-aminopropyl) piperidine, 4-(2-aminoethyl)morpholine or 1-(2-aminoethyl)piperidine, aliphatic or aromatic aldehyde and thiosalicylic acid, were synthesized in good yields by multicomponent one-pot reactions. The solvent was toluene and this efficient...