Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis

• Main Authors: Rui Chen (Author), Jingran Zeng (Author), Chuting Li (Author), Haiming Xiao (Author), Shanshan Li (Author), Zeyuan Lin (Author), Kaipeng Huang (Author), Juan Shen (Author), Heqing Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic nephropathy (DN) is quickly becoming the largest cause of end-stage renal disease (ESRD) in diabetic patients, as well as a major source of morbidity and mortality. Our previous studies indicated that the activation of Nrf2/ARE pathway via Connexin43 (Cx43) considerably contribute to the pr...