The efficacy and safety of a nicotine conjugate vaccine (NicVAX^®) or placebo co-administered with varenicline (Champix^®) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial

• Main Authors: Hoogsteder Philippe HJ (Author), Kotz Daniel (Author), van Spiegel Paul I (Author), Viechtbauer Wolfgang (Author), Brauer Ruth (Author), Kessler Paul D (Author), Kalnik Matthew W (Author), Fahim Raafat EF (Author), van Schayck Onno CP (Author)
• Format: Book
• Published: BMC, 2012-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>A potential new treatment in smoking cessation and relapse prevention is nicotine vaccination which is based on active immunization against the nicotine molecule. This immunization will elicit the immune system to produce nicotine-sp...