Liquid chromatographyâtandem mass spectrometry method for the estimation of adefovir in human plasma: Application to a pharmacokinetic study

• Main Authors: Dipanjan Goswami (Author), Sanjay Gurule (Author), Arabinda Saha (Author), Poonam Vats (Author), Arshad Khuroo (Author), Tausif Monif (Author)
• Format: Book
• Published: Elsevier, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An analytical method based on solid phase extraction was developed and validated for analysis of adefovir in human plasma. Adefovir-d4 was used as an internal standard and Synergi MAX RP80A (150 mmÃ4.6 mm, 4 µm) column provided the desired chromatographic separation of compounds followed by dete...