Pharmacokinetics, metabolite profiling, safety and tolerability of YZJ-4729 tartrate, a novel G protein-biased μ-opioid receptor agonist, in healthy Chinese subjects

• 主要な著者: Yufeng Ni (著者), Huaye Gao (著者), Wen Ouyang (著者), Guoping Yang (著者), Minlu Cheng (著者), Li Ding (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Objective: YZJ-4729 is a novel G protein-biased μ-opioid receptor agonist for the treatment of acute pain in adult patients who require intravenous opioid analgesic therapy. The aim of this study was to assess the pharmacokinetics, metabolite profiling, safety and tolerability of YZJ-4729 in healthy...