An open, non-randomised, phase 1/2 trial on the safety, tolerability, and immunogenicity of single-dose vaccine "Sputnik Light" for prevention of coronavirus infection in healthy adults

• Main Authors: Amir I. Tukhvatulin (Author), Inna V. Dolzhikova (Author), Dmitry V. Shcheblyakov (Author), Olga V. Zubkova (Author), Alina S. Dzharullaeva (Author), Anna V. Kovyrshina (Author), Nadezhda L. Lubenets (Author), Daria M. Grousova (Author), Alina S. Erokhova (Author), Andrei G. Botikov (Author), Fatima M. Izhaeva (Author), Olga Popova (Author), Tatiana A. Ozharovskaia (Author), Ilias B. Esmagambetov (Author), Irina A. Favorskaya (Author), Denis I. Zrelkin (Author), Daria V. Voronina (Author), Dmitry N. Shcherbinin (Author), Alexander S. Semikhin (Author), Yana V. Simakova (Author), Elizaveta A. Tokarskaya (Author), Maksim M. Shmarov (Author), Natalia A. Nikitenko (Author), Vladimir A. Gushchin (Author), Elena A. Smolyarchuk (Author), Tatiana G. Zubkova (Author), Konstantin A. Zakharov (Author), Vasiliy B. Vasilyuk (Author), Sergei V. Borisevich (Author), Boris S. Naroditsky (Author), Denis Y. Logunov (Author), Alexander L. Gintsburg (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: While the world is experiencing another wave of COVID-19 pandemic, global vaccination program is hampered by an evident shortage in the supply of licensed vaccines. In an effort to satisfy vaccine demands we developed a new single-dose vaccine based on recombinant adenovirus type 26 (rAd...