The Leukemic Stem Cell Niche: Adaptation to "Hypoxia" versus Oncogene Addiction

The Leukemic Stem Cell Niche: Adaptation to "Hypoxia" versus Oncogene Addiction

Previous studies based on low oxygen concentrations in the incubation atmosphere revealed that metabolic factors govern the maintenance of normal hematopoietic or leukemic stem cells (HSC and LSC). The physiological oxygen concentration in tissues ranges between 0.1 and 5.0%. Stem cell niches (SCN)...

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Main Authors: Giulia Cheloni (Author), Martina Poteti (Author), Silvia Bono (Author), Erico Masala (Author), Nathalie M. Mazure (Author), Elisabetta Rovida (Author), Matteo Lulli (Author), Persio Dello Sbarba (Author)
Format: Book
Published: Hindawi Limited, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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