Orphan drugs' clinical uncertainty and prices: Addressing allocative and technical inefficiencies in orphan drug reimbursement

• Main Authors: Hans-Georg Eichler (Author), Michael Kossmeier (Author), Markus Zeitlinger (Author), Brigitte Schwarzer-Daum (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Legislations incentivising orphan drug development and scientific advances have made orphan drugs pharma's high-end favourite for the past two decades. Currently, around 50% of new marketing authorizations are for orphan drugs. For third-party healthcare payers ("payers") the rise of...