Molecular identification of HLA‐B75 serotype markers by qPCR: A more inclusive pharmacogenetic approach before carbamazepine prescription

• Main Authors: Kanoot Jaruthamsophon (Author), Pornsiri Sangmanee (Author), Oradawan Plong‐on (Author), Chariyawan Charalsawadi (Author), Chonlaphat Sukasem (Author), Areerat Hnoonual (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Genetic screening for HLA‐B*15:02 before prescribing carbamazepine is standard practice to prevent severe cutaneous adverse reactions in Asian populations. These reactions are associated not only with this allele but also with closely related HLA‐B75 serotype markers-HLA‐B*15:11 and HLA‐B*1...