Screening of anti-inflammatory activity of 4.5-dihydroisoxazol-5-carboxamide (PAR-2 inhibitors) based on formaldehyde oedema model among white lab rats

• Main Authors: Mikhail K. Korsakov (Author), Vladimir N. Fedorov (Author), Nikolay A. Smirnov (Author), Anton A. Shetnev (Author), Olga V. Leonova (Author), Nikita N. Volkhin (Author), Aleksandr I. Andreyev (Author)
• Format: Book
• Published: Belgorod National Research University, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Rheumatoid arthritis (RА) is an immune-inflammatory disease intrinsic to up to 1.0% of the world's population. Standard drugs for RA therapy are basic medications, glucocorticoids and non-steroid anti-inflammatory drugs, which often only ease or hinder the course of disease, not c...