Conditional reprogramming: next generation cell culture

• Main Authors: Xiaoxiao Wu (Author), Shengpeng Wang (Author), Mingxing Li (Author), Jing Li (Author), Jing Shen (Author), Yueshui Zhao (Author), Jun Pang (Author), Qinglian Wen (Author), Meijuan Chen (Author), Bin Wei (Author), Parham Jabbarzadeh Kaboli (Author), Fukuan Du (Author), Qijie Zhao (Author), Chi Hin Cho (Author), Yitao Wang (Author), Zhangang Xiao (Author), Xu Wu (Author)
• Format: Book
• Published: Elsevier, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Long-term primary culture of mammalian cells has been always difficult due to unavoidable senescence. Conventional methods for generating immortalized cell lines usually require manipulation of genome which leads to change of important biological and genetic characteristics. Recently, conditional re...