Cytostatic Action of Novel Histone Deacetylase Inhibitors in Androgen Receptor-Null Prostate Cancer Cells

Androgen receptor (AR)-null prostate tumors have been observed in 11-24% of patients. Histone deacetylases (HDACs) are overexpressed in prostate tumors. Therefore, HDAC inhibitors (Jazz90 and Jazz167) were examined in AR-null prostate cancer cell lines (PC3 and DU145). Both Jazz90 and Jazz167 inhibi...

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Main Authors: Zohaib Rana (Author), Joel D. A. Tyndall (Author), Muhammad Hanif (Author), Christian G. Hartinger (Author), Rhonda J. Rosengren (Author)
Format: Book
Published: MDPI AG, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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