Pharmacological Aspects of the Effects of Tramadol on G-Protein Coupled Receptors

• Huvudskapare: Kouichiro Minami (Författare, medförfattare), Yasuhito Uezono (Författare, medförfattare), Yoichi Ueta (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Elsevier, 2007-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Tramadol is an analgesic that is used worldwide, but its mechanisms of action have not been elucidated. It has been speculated that tramadol acts primarily through the activation of µ-opioid receptors and the inhibition of monoamine reuptake. The majority of studies to date have focused on ion chann...