Trimethoprim Use prior to Pregnancy and the Risk of Congenital Malformation: A Register-Based Nationwide Cohort Study

• Main Authors: Jon Trærup Andersen (Author), Morten Petersen (Author), Espen Jimenez-Solem (Author), Jeppe Nørgaard Rasmussen (Author), Nadia Lyhne Andersen (Author), Shoaib Afzal (Author), Kasper Broedbaek (Author), Brian Rafn Hjelvang (Author), Lars Køber (Author), Christian Torp-Pedersen (Author), Henrik Enghusen Poulsen (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives. The aim of the study was to investigate whether the use of the antifolate antibiotic trimethoprim during the 12 weeks before conception was associated with congenital malformations. Methods. We conducted a nationwide register-based cohort study including all Danish women giving birth fro...