Oromucosal Alginate Films with Zein Nanoparticles as a Novel Delivery System for Digoxin

• Main Authors: Daniela A. Rodrigues (Author), Sónia P. Miguel (Author), Jorge Loureiro (Author), Maximiano Ribeiro (Author), Fátima Roque (Author), Paula Coutinho (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Digoxin is a hydrophobic drug used for the treatment of heart failure that possesses a narrow therapeutic index, which raises safety concerns for toxicity. This is of utmost relevance in specific populations, such as the elderly. This study aimed to demonstrate the potential of the sodium alginate f...