Advanced glycation end product-modified low-density lipoprotein promotes pro-osteogenic reprogramming via RAGE/NF-κB pathway and exaggerates aortic valve calcification in hamsters

• Main Authors: Xi Yang (Author), Jingxin Zeng (Author), Kaiji Xie (Author), Shuwen Su (Author), Yuyang Guo (Author), Hao Zhang (Author), Jun Chen (Author), Zhuang Ma (Author), Zezhou Xiao (Author), Peng Zhu (Author), Shaoyi Zheng (Author), Dingli Xu (Author), Qingchun Zeng (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Advanced glycation end product-modified low-density lipoprotein (AGE-LDL) is related to inflammation and the development of atherosclerosis. Additionally, it has been demonstrated that receptor for advanced glycation end products (RAGE) has a role in the condition known as calcif...