Synergistic Antiproliferation of Cisplatin and Nitrated [6,6,6]Tricycle Derivative (SK2) for a Combined Treatment of Oral Cancer Cells

• Main Authors: Sheng-Chieh Wang (Author), Ching-Yu Yen (Author), Jun-Ping Shiau (Author), Meng-Yang Chang (Author), Ming-Feng Hou (Author), Jiiang-Huei Jeng (Author), Jen-Yang Tang (Author), Hsueh-Wei Chang (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SK2, a nitrated [6,6,6]tricycle derivative with an <i>n</i>-butyloxy group, showed selective antiproliferation effects on oral cancer but not on normal oral cells. This investigation assessed for the first time the synergistic antiproliferation potential of cisplatin/SK2 in oral cancer c...