Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells

• Main Authors: Elena Gazzano (Author), Loretta Lazzarato (Author), Barbara Rolando (Author), Joanna Kopecka (Author), Stefano Guglielmo (Author), Costanzo Costamagna (Author), Konstantin Chegaev (Author), Chiara Riganti (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antitumor chemotherapy remains one of the most important challenge of the medicinal chemistry. Emerging research in chemotherapy is focused on exploiting the biochemical differences between cancer cell and normal cell metabolism in order to reduce the side effects and increase antitumor therapy effi...