Population pharmacokinetic study of the effect of polymorphisms in the ABCB1 and CES1 genes on the pharmacokinetics of dabigatran

• প্রধান লেখক: Zhuan Yang (লেখক), Wen Rui Tan (লেখক), Qin Li (লেখক), Ying Wang (লেখক), Shijing Liu (লেখক), Lu Chen (লেখক), Yan Zhou (লেখক), Chen Zeng (লেখক), Yan Zeng (লেখক), Yun Xiong (লেখক), Qian Zhang (লেখক), Na Li (লেখক), Peng Du (লেখক), Lin Liu (লেখক), Jiyu Chen (লেখক), Yan He (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

PurposeThe impact of genetic polymorphisms in the ABCB1 and CES1 genes on dabigatran plasma concentrations remains a subject of debate, and the purpose of this study was to quantitatively assess the effects of genetic polymorphisms on dabigatran esters in healthy Chinese subjects employed a populati...