Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

• Main Authors: Puvanesswaray Ramakrishnan (Author), Wei Mee Loh (Author), Subash C.B. Gopinath (Author), Srinivasa Reddy Bonam (Author), Ismail M. Fareez (Author), Rhanye Mac Guad (Author), Maw Shin Sim (Author), Yuan Seng Wu (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activated pancreatic stellate cells (PSCs) have been widely accepted as a key precursor of excessive pancreatic fibrosis, which is a crucial hallmark of chronic pancreatitis (CP) and its formidable associated disease, pancreatic cancer (PC). Hence, anti-fibrotic therapy has been identified as a nove...