The impact of proline isomerization on antigen binding and the analytical profile of a trispecific anti-HIV antibody

Proline cis-trans conformational isomerization is a mechanism that affects different types of protein functions and behaviors. Using analytical characterization, structural analysis, and molecular dynamics simulations, we studied the causes of an aberrant two-peak size-exclusion chromatography profi...

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Main Authors: Alessandro Masiero (Author), Lechat Nelly (Author), Gentric Marianne (Author), Sourrouille Christophe (Author), Laville Florian (Author), Crépin Ronan (Author), Borel Claire (Author), Ziegler Cornelia (Author), Bisch Grégoire (Author), Leclerc Eric (Author), Laurent Ludovic (Author), Brault Dominique (Author), Alexandre Sylvie (Author), Gagnaire Marie (Author), Duffieux Francis (Author), Soubrier Fabienne (Author), Capdevila Cécile (Author), Arnould Isabelle (Author), Dumas Jacques (Author), Dabin Jérôme (Author), Genet Bruno (Author), Radošević Katarina (Author), Menet Jean-Michel (Author), Prades Catherine (Author)
格式: 圖書
出版: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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索引號: A1234.567
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