Xanthohumol, a Prenylated Flavonoid from Hops, Induces Caspase-Dependent Degradation of Oncoprotein BCR-ABL in K562 Cells

BCR-ABL oncoprotein drives the initiation, promotion, and progression of chronic myelogenous leukemia (CML). Tyrosine kinase inhibitors are the first choice for CML therapy, however, BCR-ABL mediated drug resistance limits its clinical application and prognosis. A novel promising therapeutic strateg...

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Main Authors: Xuxiu Lu (Author), Jiajia Geng (Author), Jinman Zhang (Author), Jinlai Miao (Author), Ming Liu (Author)
Format: Book
Published: MDPI AG, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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