Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system

• Main Authors: Jiaqi Chen (Author), Zhuoying He (Author), Wenjuan Xu (Author), Yumiao Kang (Author), Fengyu Zhu (Author), Heng Tang (Author), Jianye Wang (Author), Fei Zhong (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mesenchymal stem cells (MSCs) have shown potential in repairing chemotherapy-induced premature ovarian failure (POF). However, challenges such as stem cell loss and immune phagocytosis post-transplantation hinder their application. Due to easy and safe handling, in vitro ovarian...