Nanoparticle-based delivery enhances anti-inflammatory effect of low molecular weight heparin in experimental ulcerative colitis

• Hoofdauteurs: Tawfek Yazeji (Auteur), Brice Moulari (Auteur), Arnaud Beduneau (Auteur), Valentin Stein (Auteur), Dirk Dietrich (Auteur), Yann Pellequer (Auteur), Alf Lamprecht (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Epithelial administration of low molecular weight heparin (LMWH) has proven its therapeutic efficiency in ulcerative colitis (UC) but still lacks of a sufficiently selective drug delivery system. Polymeric nanoparticles were used here not only to protect LMWH from intestinal degradation but also to...