Rationale and Design of the First Double-Blind, Placebo-Controlled Trial with Allogeneic Adipose Tissue-Derived Stromal Cell Therapy in Patients with Ischemic Heart Failure: A Phase II Danish Multicentre Study

• Main Authors: Jens Kastrup (Author), Morten Schou (Author), Ida Gustafsson (Author), Olav W. Nielsen (Author), Rasmus Møgelvang (Author), Klaus F. Kofoed (Author), Charlotte Kragelund (Author), Jens Dahlgaard Hove (Author), Andreas Fabricius-Bjerre (Author), Merete Heitman (Author), Mandana Haack-Sørensen (Author), Lisbeth Drozd Lund (Author), Ellen Mønsted Johansen (Author), Abbas Ali Qayyum (Author), Anders Bruun Mathiasen (Author), Annette Ekblond (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Ischemic heart failure (IHF) has a poor prognosis in spite of optimal therapy. We have established a new allogeneic Cardiology Stem Cell Centre adipose-derived stromal cell (CSCC_ASC) product from healthy donors. It is produced without animal products, in closed bioreactor systems and cr...